accumulation of adenosine is strongly correlated with the need for sleep and the detection of sleep pressure is antagonised by caffeine. 9 Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK. 8 Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK.7 Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.6 Department of Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA.5 Sleep and Circadian Neuroscience Institute (SCNi), Department of Pharmacology, University of Oxford, Oxford, UK.4 Department of Molecular Biology, University of Geneva, Geneva 4, Switzerland.3 Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK.2 Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK. 1 Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, University of Oxford, OMPI-G, Oxford, UK.
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